科學+家 高濃参碱蜂膠液 | SCIENTIST HOME Matrine Propolis

蜂膠

蜂膠是一種天然的樹脂混合物，由蜜蜂從植物的某些部位、芽和分泌物中選取物質製成。由於蜂膠的蠟質和機械特性，蜜蜂在建造和修理蜂箱時使用蜂膠來密封開口和裂縫，平滑內壁，並作為抵禦外來入侵物（如蛇、蜥蜴等）或抵禦風雨等風化威脅的保護屏障。蜜蜂採集的蜂膠來自不同的植物，在溫帶氣候區主要來自楊樹。蜂膠現時的抗菌應用包括感冒綜合征（上呼吸道感染、普通感冒和流感樣感染）、傷口癒合、燒傷、痤瘡、單純皰疹和生殖器以及神經性皮炎的治療。

参碱

近年來，體外和體內研究表明，参碱在5至2000 ng/mL之間呈線性藥代動力學（Zhang X.L.等人，2009），並具有廣泛的藥理作用，包括抗癌、抗炎、抗菌、抗寄生蟲、抗病毒、抗纖維化和鎮靜特性。 這些藥理作用已被用於治療肝炎（Gong等人，2015年）； 心臟病（Liu等人，2017b）； 皮膚病（Liu J.Y.et al.，2007）和許多癌症，如肝細胞癌（Wang L.et al.，2013）； 胃癌（Luo等人，2007年）； 乳腺癌（Zhou B.G.et al.，2017）和胰腺癌（Huang和Xin，2017）。 之前的綜述報導了参碱的化學成分和抗癌特性（Huang和Xu，2016）。

越來越多的證據顯示濫用抗生素的負面影響，包括誘導免疫力下降和細菌失調。 参碱具有抗炎、抗病毒和抗菌等多種有益作用。参碱顯著增加了有益細菌的比例，如反芻梭狀芽孢杆菌9、乳螺科細菌NK4A136和未分類的反芻科細菌。 綜上所述，服用阿莫西林可以通過新增病原菌與有益菌的比例來改變微生物群落的組成和結構，而参碱可以新增有益菌的數量。 此外，本研究為尋找抗生素替代品以降低細菌耐藥性和腸道菌群失衡提供了理論依據。對分離出的参類生物碱進行抗乙型肝炎病毒活性評估，化合物1、4、5、10和14顯示出與参碱相當的抗病毒效力。

科學+家 高濃参碱蜂膠液/20毫升/水劑/瓶裝

特色： 蜂膠含黃酮類化合物、多種天然胺基酸、維他命和人體必需的微量元素等等，有助迅速癒合傷口、促進細胞再生。長期食用蜂膠亦有助強身健體。

可能適合多學科復康調理:

外用: 口瘡（1）、傷口癒合（18）、燒傷（19）、痤瘡（20）單純皰疹（21）灰甲(24) 抗微生物(6,8)、抗真菌(7)、

內服: 胃潰瘍（2）、喉嚨痛（3）、久咳（4）、上呼吸道感染(5)、抗微生物(6,8)、抗真菌(7)、抗原蟲(9,10)、抗肿瘤活性(11,12,13,14,)、哮喘(15)、普通感冒(16)、 流感样感染(17)、危疾（22,23）寄生蟲(25,26,27)

用法：

內服: 每日三次，每次3至10滴；仰頭滴入咽喉吞下, 10分鐘後再以溫開水送服；

外用: 以棉棒沾上蜂膠再塗於口腔內 或皮膚需要的位置。

成分： 蜂膠，参碱、純水

注意事項：

• 過敏原：含有蜜蜂產品, 個別人士可能對蜜蜂產品、蜂膠有過敏反應。如屬初次食用，建議可先試塗一滴在手背皮膚上，5分鐘後抺去，如沒出現過敏發紅，則適合食用；如有過敏發紅則不宜食用！
• 請注意孕婦及嬰兒不能食用参碱蜂膠。

溫馨提示：

• 本品為食物補充劑，不能代替藥物
• 如有不適反應，建議停止服用
• 嬰幼兒、妊娠期、哺乳期婦女不能食用参碱蜂膠液 (請選購酸酯蜂膠液)
• 如不瞭解問題原因或問題持續，請儘快諮詢醫生
• 本品不能以金屬容器盛載，以免影響質量。

儲存方法：請存放在陰涼乾燥

產地: 中國香港

如你有任何疾病, 請遵照閣下醫生的完整醫療方案; 而是否使用多學科復康方案前, 你必須咨詢主診醫生的意見, 如果閣下的主診醫生不建議您加入補充劑調理組合, 請你不要使用。如果你需要尋求其他醫生作第二咨詢, 閣下可聯絡我們線上<無邊界醫生>或你自己城市內的其他專業醫生的再診斷。

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Propolis

Propolis is a natural resin mixture, which is made by bees from certain parts of plants, buds and secretions. Due to the wax and mechanical properties of propolis, bees use propolis to seal openings and cracks, smooth the inner wall, and act as a protective barrier against foreign invaders (such as snakes, lizards, etc.) or weathering threats such as wind and rain when building and repairing beehives. Bees collect propolis from different plants, mainly from poplar in temperate climate. The current antibacterial applications of propolis include the treatment of cold syndrome (upper respiratory tract infection, common cold and influenza like infection), wound healing, burns, acne, herpes simplex and genitalia, and neurodermatitis.

SCIENTIST HOME Matrine Propolis

Features: Propolis contains flavonoids, a variety of natural amino acids, vitamins and trace elements necessary for human body, etc. which help to heal wounds quickly and promote cell regeneration. Long term consumption of propolis also helps to strengthen the body.

Suggested multidisciplinary rehabilitation:

External use: aphthous ulcer (1), wound healing (18), burn (19), acne (20), herpes simplex (21), grey nail (24), antimicrobial (6,8), antifungal (7)

Oral administration: gastric ulcer (2), sore throat (3), long cough (4), upper respiratory tract infection (5), antimicrobial (6,8), antifungal (7), antigenic insects (9,10), antitumor activity (11,12,13,14,), asthma (15), common cold (16), influenza like infection (17), dangerous diseases (22,23) parasites (25,26,27)

Consumption:

a) Oral intake: 3 times a day, 3 to 10 drops each time; drop it into the throat with head up, to be followed with warm water after 10 minutes;

b) External use: Dip propolis with cotton swab, and then apply it to affected area of mouth or skin.

Caution/Allergen:

• Contains bee products; individual may have allergic reaction to bee products or propolis. If it's for the first time, suggest to apply a drop on the skin on the back of the hand, and remove it after 5 minutes. If there is no allergic redness, it's deemed suitable for consumption; if there is allergic redness, please do not consume.
• Please note that propolis is not suitable for pregnant women and infants.

• This product is a food supplement and cannot replace drugs
• In case of discomfort, please stop taking
• Not suitable for infants, pregnant or lactating women (please opt for EGCG Propolis)
• If you do not know the cause of health condition or the problem persists, please consult your doctor as soon as possible
• This product cannot be contained in metal containers, so as not to affect the quality

Country of Origin: Hong Kong, China

If you have a medical condition, please follow your doctor's medical treatment plan. Do consult your medical doctor before using the Multidisciplinary Rehabilitation Program (MRP). Please do not proceed if your medical doctor does not recommend the use of our MRP. If you'd like to seek a second opinion from other doctors, you may contact our online "Doctors Without Border", or other professional doctors at your convenience.

Ref / 參考研究:

1. Nachum Samet ¹ , Caroline Laurent, Srinivas M Susarla, Naama Samet-Rubinsteen The effect of bee propolis on recurrent aphthous stomatitis: a pilot study Clin Oral Investig . 2007 Jun;11(2):143-7. doi: 10.1007/s00784-006-0090-z. Epub 2007 Feb 7. PMID: 17285269 . DOI: 10.1007/s00784-006-0090-z
2. Luísa Silva, Priscila de Souza, Soad Khalil AL Jaouni, Steve Harakeh. Propolis and Its Potential to Treat Gastrointestinal DisordersMarch 2018, Evidence-based Complementary and Alternative Medicine 2018(7):1-12, DOI: 10.1155/2018/2035820
3. Vijay D. Wagh, Propolis: A Wonder Bees Product and Its Pharmacological Potentials. Adv Pharmacol Sci. 2013; 2013: 308249. Published online 2013 Dec 9. doi: 10.1155/2013/308249. PMCID: PMC3872021. PMID: 24382957
4. Ibrahim Alfahdawi. Propolis In Medicine & Dentistry. April 2017. Edition: 1. Publisher: LAMBERT Academic Publishing. Editor: Dr. Wolfgang Philipp Muller
5. Vijay D. Wagh, "Propolis: A Wonder Bees Product and Its Pharmacological Potentials", Advances in Pharmacological and Pharmaceutical Sciences, vol. 2013, Article ID 308249, 11 pages, 2013. https://doi.org/10.1155/2013/308249
6. Nilesh Kumar*, Mueen Ahmad K. K., Raman Dang and Ahmed Husain. Department of Pharmacognosy, Al-Ameen College of Pharmacy, Hosur road, Bangalore. Antioxidant and antimicrobial activity of Propolis from Tamil Nadu zone. Article Number - C57754015645.Vol.2(12), pp. 361-364 , December 2008. https://doi.org/10.5897/JMPR.9000208
7. Ayşe Nedret Koç, Sibel Silici, Filiz Kasap, Hatice Tuna Hörmet-Öz, Hikmet Mavus-Buldu, and Barış Derya Ercal. Antifungal Activity of the Honeybee Products Against Candida spp. and Trichosporon spp. Journal of Medicinal FoodVol. 14, No. 1-2 Full Communications. Published Online:18 Jan 2011. https://doi.org/10.1089/jmf.2009.0296
8. J M Grange MSc MD, R W Davey, MFHom. Antibacterial Properties of Propolis (Bee Glue) . https://doi.org/10.1177/014107689008300310
9. Kelly Salomão, Eniuce M. de Souza, Andrea Henriques-Pons, Helene S. Barbosa, Solange L. de Castro, "Brazilian Green Propolis: Effects In Vitro and In Vivo on Trypanosoma cruzi", Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 185918, 11 pages, 2011. https://doi.org/10.1093/ecam/nep014
10. Torres, D. ; Hollands, I. ; Palacios, E. Effect of an alcoholic extract of propolis on the in vitro growth of Giardia lamblia. Journal article : Revista Cubana de Ciencias Veterinarias 1990 Vol.21 No.1 pp.15-19
11. Mok-RyeonAhn^aKazuhiroKunimasa^b ToshiroOhta^b ShigenoriKumazawa^a MiyaKamihira^aKazuhikoKaji^b YoshihiroUto^c HitoshiHori^c HidekoNagasawa^d TsutomuNakayama^a. Suppression of tumor-induced angiogenesis by Brazilian propolis: Major component artepillin C inhibits in vitro tube formation and endothelial cell proliferation. Cancer Letters Volume 252, Issue 2, 18 July 2007, Pages 235-243. https://doi.org/10.1016/j.canlet.2006.12.039
12. Oršolić, Nada ; Bendelja, Krešo ; Brbot– ; Šaranović, Ana ; Bašić, Ivan. Effect of caffeic acid phenethyl ester and caffeic acid, an antioxidant from propolis, on inducing apoptosis in HeLa human cervical carcinoma and Chinese hamster lung V79 fibroblast cells. Periodicum biologorum (0031-5362) 106 (2004); 367-372
13. Chemical diversity of propolis makes it a valuable source of new biologically active compounds. Journal of ApiProduct and ApiMedical Science 1 (2): 23 - 28 (2009). DOI 10.3896/IBRA.4.01.2.01.
14. Nada Oršolić, Svjetlana Terzić, Željko Mihaljević, Lidija Šver, Ivan Bašić. Effects of Local Administration of Propolis and Its Polyphenolic Compounds on Tumor Formation and Growth. 2005 Volume 28 Issue 10 Pages 1928-1933. DOI https://doi.org/10.1248/bpb.28.1928
15. M T Khayyal ¹ , M A el-Ghazaly, A S el-Khatib, A M Hatem, P J F de Vries, S el-Shafei, M M Khattab. A clinical pharmacological study of the potential beneficial effects of a propolis food product as an adjuvant in asthmatic patients. . 2003 Feb;17(1):93-102. doi: 10.1046/j.1472-8206.2003.00117.x. PMID: 12588635
16. A. Ohkuma, T. Kanno, T. Asama, S. Doi-Takaki. Effect of dietary supplement containing brazilian propolis on the common cold. January 2010. Pharmacometrics 79(3):43-48.
17. Ali Farid M. Ali, Ermelando V. Cosmi, Sanaa M. Al and Laila Farid. Bee propolis as a new modality for treatment of H1N1 Influenza. J Am Sci 2013;9(34):261-264]. (ISSN: 1545-1003).http://www.jofamericanscience.org. 34
18. AhmadOryan^a, EsmatAlemzadeh^b, AliMoshiri^c. Potential role of propolis in wound healing: Biological properties and therapeutic activities. Biomedicine & Pharmacotherapy. Volume 98, February 2018, Pages 469-483. https://doi.org/10.1016/j.biopha.2017.12.069
19. Paweł Olczyk, ^{1 , *} Robert Koprowski, ² Justyna Kaźmierczak, ³ Lukasz Mencner, ³ Robert Wojtyczka, ⁴ Jerzy Stojko, ⁵ Krystyna Olczyk, ³ and Katarzyna Komosinska-Vassev ³ Bee Pollen as a Promising Agent in the Burn Wounds Treatment. Journal ListEvid Based Complement Alternat Medv.2016; 2016. PMC4887649 Evid Based Complement Alternat Med. 2016; 2016: 8473937. Published online 2016 May 18. doi: 10.1155/2016/8473937 PMCID: PMC4887649 PMID: 27293466.
20. Basma M Mohammad Ali¹, Naglaa F Ghoname², Abeer A Hodeib MD ¹, Marwa A Elbadawy¹
    Department of Dermatology and Venereology, Tanta University, Tanta, Egypt. Significance of topical propolis in the treatment of facial acne vulgaris. DOI: 10.4103/1110-6530.162468
21. Silke Nolkemper,Jürgen Reichling,Karl Heinz Sensch,Paul Schnitzler September 2009. Mechanism of herpes simplex virus type 2 suppression by propolis extracts. 17(2):132-8. Phytomedicine: International Journal of Phytotherapy and PhytopharmacologyI: 10.1016/j.phymed.2009.07.006
22. Patricia Vit, Fazlul Huq, Ortrud Monika Barth, Mercedes Campo. Use of Propolis in Cancer Research. April 2015.British Journal of Medicine and Medical Research 8(2):88-109. DOI: 10.9734/BJMMR/2015/16216
23. Pongsathon Premratanachai¹ and Chanpen Chanchao^2,. Review of the anticancer activities of bee products. Asian Pac J Trop Biomed. 2014 May; 4(5): 337–344. doi: 10.12980/APJTB.4.2014C1262. PMCID: PMC3985046. PMID: 25182716.
24. Flavia Franco Veiga,1,2 Maiara Ignacio Costa,1,3 Érika Seki Kioshima Cótica,1 Terezinha Inez Estivalet Svidzinski,1 and Melyssa Negri1.Propolis for the Treatment of Onychomycosis. Journal List. Indian J Dermatol. v.63(6); Nov-Dec 2018. PMC6233048. Indian J Dermatol. 2018 Nov-Dec; 63(6): 515–517. doi: 10.4103/ijd.IJD_365_17.PMID: 30504984
25. C Miyares 1 , I Hollands, C Castañeda, T González, T Fragoso, R Currás, C Soria. Clinical trial with a preparation based on propolis "propolisina" in human giardiasis. Clinical Trial Acta Gastroenterol Latinoam. 1988;18(3):195-201. PMID: 3077894
26. Jéssica Rebouças-Silva,1,2 Fabiana S. Celes,1 Jonilson Berlink Lima,3 Hernane S. Barud ,4,5 Camila I. de Oliveira ,1 Andresa A. Berretta ,6,7 and Valéria M. Borges 1,2. Parasite Killing of Leishmania (V) braziliensis by Standardized Propolis Extracts. Evidence-Based Complementary and Alternative Medicine / 2017 / Article. Research Article | Open Access
    Volume 2017 |Article ID 6067172 | https://doi.org/10.1155/2017/6067172
27. S.F. Freitas. L Shinohara. José Maurício Sforcin. In vitro effects of propolis on Giardia duodenalis trophozoites. March 2006Phytomedicine 13(3):170-5. DOI: 10.1016/j.phymed.2004.07.008

本品等並非根據《藥劑業及毒藥條例》或《中醫藥條例》注册。 任何對其提出的宣稱均不受此類登記評估的約束。 本產品不用於診斷、治療或預防任何疾病。

This product is not registered under the Pharmacy and Poisons Ordinance or the Chinese Medicine Ordinance. Any claim made for it has not been subject to evaluation for such registration. This product is not intended to diagnose, treat or prevent any disease.