體重問題 | Weight Problem

Store/體重問題 | Weight Problem

體重問題

肥胖和胰島素抵抗在多囊卵巢綜合征（PCOS）發病或維持不良健康中起重要作用。這意味著減輕體重和胰島素抵抗的治療可以減輕多囊卵巢綜合征的症狀。生活方式的改變被發現能有效地恢復80%的人的生殖功能，這些人的體重至少減輕了5%。然而，長期保持體重是一個挑戰。本文綜述了降低血糖負荷飲食，包括低血糖指數、極低碳水化合物、高蛋白和高單不飽和脂肪飲食對多囊卵巢綜合征和非多囊卵巢綜合征人群代謝和生殖健康的影響。對非多囊卵巢綜合征婦女的飲食試驗表明，高蛋白、降低血糖負荷的飲食可能比傳統的低脂、高碳水化合物飲食更有益，但對多囊卵巢綜合征婦女的這一點尚需進一步研究證實。同樣，PCOS婦女的最佳運動方案仍有待研究。 (1)

肌醇與女性體重的關係:

  • 顯著降低 BMI、W:H比值、舒張壓、空腹血糖(2)
  • 加速减重和减脂(3)
  • BMI、腰围、臀围均显著下降(4)
  • 肌醇也可以作为二甲双胍治疗多囊卵巢综合征的替代品(5)


Weight Problem

Obesity and insulin resistance play an important role in initiating or maintaining ill health in polycystic ovary syndrome (PCOS). This implies that treatment that reduces body weight and insulin resistance would alleviate the symptoms of PCOS. Lifestyle modification has been found to be effective in restoring reproductive function in up to 80% of individuals who achieve at least 5% weight loss. However, long-term weight maintenance is a challenge. This article provides a review of reduced glycemic load diets, including low glycemic index, very low carbohydrate, high-protein and high monounsaturated fat diets, on metabolic and reproductive health in PCOS and non-PCOS populations. Dietary trials in non-PCOS women suggest that higher-protein, reduced glycemic load diets were probably more beneficial than the conventional low-fat, high-carbohydrate diet but further studies are required to confirm this in PCOS women. Similarly, the optimal exercise regime for PCOS women remains to be investigated.(1)


The relationship between inositol and female body weight was as follows:

  • Significantly reduced BMI, W: H ratio, diastolic blood pressure and fasting blood glucose (2)
  • Accelerated weight loss and fat loss (3)
  • BMI, waist circumference and hip circumference decreased significantly (4)
  • Inositol can also be used as a substitute for metformin in the treatment of polycystic ovary syndrome (5)


Refs:

  1. Siew S Lim†, Peter M Clifton, Manny Noakes, Obesity Management in Women with Polycystic Ovary Syndrome. First Published January 1, 2007 Review Article. https://doi.org/10.2217/17455057.3.1.73
  2. Manideepa Pande, Ashish Seal, Sukanta Mishra, Arup Dasgupta, Mousumi Sengupta, Rinini Dastider. The effects of combined therapy of myo-inositol and D-chiro inositol in reduction of the individual components of metabolic syndrome in overweight PCOS patients compared to myo-inositol supplementation alone: a prospective randomised controlled trial. DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog2017291...
  3. M Le Donne 1 , D Metro, A Alibrandi, M Papa, S Benvenga. Effects of three treatment modalities (diet, myoinositol or myoinositol associated with D-chiro-inositol) on clinical and body composition outcomes in women with polycystic ovary syndrome. Eur Rev Med Pharmacol Sci. 2019 Mar;23(5):2293-2301.PMID: 30915778 DOI: 10.26355/eurrev_201903_17278
  4. Maria Le Donne, D. Metro, A. Alibrandi, M. Papa. Effects of three treatment modalities (diet, myoinositol or myoinositol associated with D-chiro-inositol) on clinical and body composition outcomes in women with polycystic ovary syndrome. March 2019. DOI: 10.26355/eurrev_201903_17278
  5. JYOTI NEHRA*, JYOTI KAUSHAL*, SAVITA RANI SINGHAL**, VEENA SINGH GHALAUT*** COMPARISION OF MYO-INOSITOL VERSUS METFORMIN ON ANTHROPOMETRIC PARAMETERS IN POLYCYSTIC OVARIAN SYNDROME IN WOMEN. International Journal of Pharmacy and Pharmaceutical Sciences. ISSN- 0975-1491 Vol 9, Issue 4, 2017
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