多囊卵巢綜合征(PCOS)是女性最常見的內分泌疾病之一,影響5-10%的育齡婦女。多囊卵巢綜合征的主要表現是高雄激素血症,主要是多毛症、尋常痤瘡、雄激素性脫髮和黑棘皮病。

目標:研究多囊卵巢綜合征患者各種皮膚表現的發生率和患病率,並將這些皮膚表現與激素變化相關聯。

設定和設計:本研究於2012年11月至2013年在一家皮膚病中心進行,為期1年。

資料和方法:現時的研究包括100名被診斷為多囊卵巢綜合征的婦女。所有病例均進行了激素分析和放射學檢查。確定皮膚表現並作出推論。

統計分析:統計分析採用卡方檢驗和獨立樣本t檢驗。在P<0.05的水准上確定了統計顯著性。

結果:在我們的研究中,多毛症、痤瘡、女性型脫髮、黑棘皮病、皮脂溢、紋和肢端絨毛的患病率分別為78%、48%、31%、30%、29%、13%和9%。

結論:多囊卵巢綜合征的皮膚學表現在診斷中起著重要的作用,並構成了多囊卵巢綜合征婦女所經歷的大部分症狀。(1)

Polycystic ovary syndrome (PCOS)

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women, affecting 5–10% of reproductive-aged women. The dermatologic manifestations of hyperandrogenism, chiefly hirsutism, acne vulgaris, androgenic alopecia, and acanthosis nigricans, are among the cardinal manifestations of PCOS.

Aim:

To study the incidence and prevalence of various cutaneous manifestations in patients with PCOS and to correlate these skin manifestations with hormonal changes.

Settings and Design:

This study was conducted at a dermatology centre over a period of 1 year from November 2012 to 2013.

Materials and Methods:

The present study included 100 women diagnosed to have PCOS. Hormonal analysis as well as radiological assessment was done in all the cases. Cutaneous manifestations were ascertained and inferences were drawn.

Statistical Analysis:

Statistical analysis was carried out by the Chi-square test and independent samples t-test. Statistical significance was determined at a level of P < 0.05.

Results:

In our study, the prevalence of hirsutism, acne, female pattern hair loss, acanthosis nigricans, seborrhea, striae and acrochordons was 78%, 48%, 31%, 30%, 29%, 13%, and 9%, respectively.

Conclusion:

Dermatologic manifestations of PCOS play a significant role in making the diagnosis and constitute a substantial portion of the symptoms experienced by women with this syndrome.(1)

Refs:

  1. Mohammad Abid Keen, Iffat Hassan Shah, and Gousia Sheikh. Cutaneous Manifestations of Polycystic Ovary Syndrome: A Cross-Sectional Clinical Study. Journal ListIndian Dermatol Online Jv.8(2); Mar-Apr 2017PMC5372429. Indian Dermatol Online J. 2017 Mar-Apr; 8(2): 104–110.
    doi: 10.4103/2229-5178.202275. PMID: 28405549